Tsukasa Nozu Selected Research

astressin

8/2022	Peripheral apelin mediates visceral hypersensitivity and impaired gut barrier in a rat irritable bowel syndrome model.
11/2018	Altered colonic sensory and barrier functions by CRF: roles of TLR4 and IL-1.
12/2017	Repeated water avoidance stress induces visceral hypersensitivity: Role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factor.

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Tsukasa Nozu Research Topics

Disease

20	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 10/2022 - 02/2015
14	Hypersensitivity (Allergy) 08/2022 - 08/2006
12	Hyperalgesia 01/2020 - 12/2014
5	Visceral Pain 07/2021 - 07/2005
4	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020 - 04/2011
4	Nociceptive Pain 01/2018 - 02/2016
2	Hypertension (High Blood Pressure) 04/2022 - 01/2008
2	Sepsis (Septicemia) 08/2021 - 12/2020
2	Bullous Pemphigoid (Pemphigoid) 10/2016 - 01/2010
1	Autistic Disorder (Autism) 10/2022
1	Fever (Fevers) 06/2022
1	Diarrhea 06/2022
1	Familial Mediterranean Fever (Periodic Disease) 06/2022
1	Dysbiosis 04/2022
1	Insulin Resistance 04/2022
1	Obesity 04/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2022
1	Dyslipidemias (Dyslipidemia) 04/2022
1	Inflammation (Inflammations) 04/2022
1	Pain (Aches) 01/2020
1	Familial cyclic vomiting syndrome 02/2014
1	Hypothyroidism 01/2011
1	Hyponatremia 01/2011
1	Thyroid Neoplasms (Thyroid Cancer) 01/2011
1	Stroke (Strokes) 01/2010
1	Hemorrhage 01/2010
1	Pyelonephritis 01/2010
1	Neoplasms (Cancer) 06/2009
1	Esophagitis 01/2008
1	Asthma (Bronchial Asthma) 01/2008
1	Hernia (Hernias) 01/2008
1	Atrophy 01/2008

Drug/Important Bio-Agent (IBA)

16	LipopolysaccharidesIBA 08/2022 - 01/2017
11	CytokinesIBA 08/2022 - 01/2017
10	Corticotropin-Releasing HormoneIBA 04/2022 - 08/2006
5	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 08/2022 - 12/2014
4	Naloxone (Narcan)FDA LinkGeneric 07/2021 - 01/2018
4	OrexinsIBA 04/2021 - 04/2011
3	astressinIBA 08/2022 - 12/2017
3	Colchicine FDA LinkGeneric 06/2022 - 12/2020
3	Toll-Like Receptor 4IBA 04/2022 - 11/2018
3	Interleukin-1 (Interleukin 1)IBA 12/2017 - 12/2015
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 08/2022 - 11/2018
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 08/2022 - 11/2018
2	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2022 - 07/2021
2	Evans Blue (Blue, Evans)FDA Link 07/2021 - 11/2020
2	Adenosine (Adenocard)FDA LinkGeneric 01/2020 - 03/2016
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2019 - 01/2018
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 12/2017 - 01/2017
1	Oxytocin (Pitocin)FDA LinkGeneric 10/2022
1	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 08/2022
1	ApelinIBA 08/2022
1	Type 2 Angiotensin ReceptorIBA 07/2021
1	PhlorhizinIBA 07/2021
1	EMA400IBA 07/2021
1	Cholinergic Agents (Cholinergics)IBA 12/2020
1	Imipramine (Janimine)FDA LinkGeneric 11/2020
1	GhrelinIBA 01/2020
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2020
1	Dopamine D2 Receptor AntagonistsIBA 01/2020
1	NeuropeptidesIBA 01/2020
1	Losartan (Cozaar)FDA LinkGeneric 01/2020
1	CB2 Cannabinoid ReceptorIBA 01/2020
1	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2020
1	Butyric Acid (Butanoic Acid)IBA 12/2019
1	Butyrates (Butyrate)IBA 12/2019
1	Grape Seed ExtractIBA 11/2019
1	Dehydroepiandrosterone SulfateIBA 06/2019
1	Dehydroepiandrosterone (DHEA)IBA 06/2019
1	Adenosine Monophosphate (AMP)IBA 01/2019
1	Protein Kinase InhibitorsIBA 01/2019
1	Pioglitazone (Actos)FDA Link 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	eritoranIBA 11/2018
1	Lovastatin (Mevacor)FDA LinkGeneric 01/2018
1	mevalonolactoneIBA 01/2018
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018
1	Liraglutide FDA Link 01/2018
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2018
1	Levodopa (L Dopa)FDA LinkGeneric 02/2016
1	CRF receptor type 1IBA 08/2015
1	Sumatriptan (Imigran)FDA LinkGeneric 02/2014
1	Peptides (Polypeptides)IBA 04/2011
1	IodineIBA 01/2011
1	Thyroid HormonesIBA 01/2011
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2010
1	Warfarin (Coumadin)FDA LinkGeneric 01/2010
1	Prednisolone (Predate)FDA LinkGeneric 01/2010
1	CalciumIBA 01/2008
1	Theophylline (Theon)FDA LinkGeneric 01/2008
1	CRF receptor type 2IBA 07/2005
1	sauvagineIBA 07/2005

Therapy/Procedure

3	Therapeutics 06/2022 - 01/2010
2	Subcutaneous Injections 01/2020 - 11/2018
2	Gastrostomy 10/2016 - 01/2010
1	Length of Stay 01/2010
1	Feeding Methods 01/2010
1	Laparotomy 06/2009